Genomic features of lung cancer patients in Indonesia’s National Cancer Center

Introduction: Advances in molecular biology bring advantages to lung cancer management. Moreover, high-throughput molecular tests are currently useful for revealing genetic variations among lung cancer patients. We investigated the genomics profile of the lung cancer patients at the National Cancer Centre of Indonesia.
Methods: A retrospective study enrolled 627 tissue biopsy samples using real time polymerase chain reaction (RT-PCR) and 80 circulating tumour DNA (ctDNA) liquid biopsy samples using next-generation sequencing (NGS) from lung cancer patients admitted to the Dharmais Cancer Hospital from January 2018 to December 2022. Data were obtained from medical records. Data statistically analysed with p<0.05 is considered significant.
Result: The EGFR test results revealed by RT-PCR were wild type (51.5%), single variant (38.8%), double variant (8.3%), and triple variant (1.4%), with 18.66% L85R, 18.22% Ex19del, and 11.08% L861Q variant. Liquid biopsy ctDNA using NGS showed only 2..., The genomics data are secondary data from third-party company (a collaborative laboratory with Dharmais Cancer Hospital), while other data are extracted from medical records from the hospital database., , This README file was generated on 2024-01-13 by Arif Riswahyudi Hanafi

## General Information

1. Title of Dataset:Genomic features of lung cancer patients in Indonesia’s National Cancer Center

2. Author Information:
Principal Investigator contact information:
Name : Arif Riswahyudi Hanafi
Institution : Dharmais Cancer Hospital, National Cancer Centre, Indonesia
E-mail :

3. Date of data collection:2018-2022

4. Geographic location of data collection:Indonesia

5. Funding sources that support the collection of data:No funding

## Data & File Overview

1. File list:
A) final_data_genomic_features_lung_cancer_indonesia.xlsx
B) README.md

2. Relationship between files, if important: None

3. Additional related data collected that was not included in the current data package: None

4. Are there multiple versions of the dataset? No

## Data Specific information

for: final_data_genomic_features_lung_cancer_indonesia.xlsx

Sheet 1: PCR
1. Number of v...