CSTF2 is correlated with prognosis and progression in hepatocellular carcinoma

The role and mechanism of CSTF2 in hepatocellular carcinoma are unclear. We constructed CSTF2 knockout HUH7 and PLC/PRF/5 cells to analyze the function of CSTF2 in liver cancer and the downstream gene changes it induces. Overall design: We established CSTF2-knockout HUH7 and PLC/PRF/5 cells and used high-throughput sequencing to analyze gene changes induced by CSTF2 downregulation.