Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, encoding for a chloride ion channel. Membrane expression of CFTR is negatively regul

NIAID Data Ecosystem70

Summary of adverse events that occurred in >5% of patients in any treatment group (treated set).

临床药物安全性

纤维化治疗

*The preferred adverse event term used for “CF exacerbation” was “cystic fibrosis.”A patient may have been counted in more than one preferred term. Percentages were calculated using the total number o

Figshare2015-12-02 更新30

peptide raw data

药物活性评估

抗菌药物联合效应

mic for the peptide and antibiotics hemolysis study combinationshplc and mass spectrum

Figshare2023-08-05 更新80

STACs suppress stimuli-induced NF-κB transcriptional activation and cytokine secretion.

NF-κB抑制剂

药物活性评估

Table shows the IC50 values of the STACs in NF-κB luciferase reporter assay and LPS-induced TNFα secretion assay.

NIAID Data Ecosystem40