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A Porphyromonas gingivalis hypothetical protein controlled by the type I-C CRISPR-Cas system is a novel adhesin important in virulence.

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP470815
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The present study demonstrates that the hypothetical protein PGN_1547 form Porphyromonas gingivalis acts as an essential virulence factor, as shown in a Galleria mellonella model for virulence. Moreover, we demonstrated that PGN_1547 is an adhesin essential in adhesion to THP-1 cells. We propose that PGN_1547 may be an essential virulence factor in P. gingivalis.
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2024-01-09
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