Pluripotency Screen Paper

NIAID Data Ecosystem2026-03-10 收录

胚胎干细胞多能性

全基因组基因筛选

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA477710 数据链接链接失效反馈

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资源简介：

Genetic screen for genes required for early embryonic pluripotency transitions.Sequencing Data from Genome-wide Knockout Screen in mESCs using the Yusa library in addition to validation sequencing data and clonal sequencing data associated with the study

创建时间：

2018-06-24

RRBS profiling and Transcriptome profiling of Stat3 wild-type, Stat3 knock-out, Dnmt3a/b wild-type and Dnmt3a/b knock-out mouse embryonic stem cells (mES cells)

表观遗传调控

胚胎干细胞多能性

Naive pluripotent epiblast cells of the preimplantation murine embryo and their in vitro counterpart, embryonic stem (ES) cells, have the capacity to give rise to all cells of the adult. Such developm

NIAID Data Ecosystem50

Transcriptomic, epigenetic and metabolic characterization of the pluripotency continuum in rabbit preimplantation embryos. Transcriptomic, epigenetic and metabolic characterization of the pluripotency continuum in rabbit preimplantation embryos

胚胎干细胞多能性

发育转录组学

Despite the growing interest in the rabbit model for developmental and stem cell biology, the characterization of embryos at the molecular level is still poorly documented. We conducted a transcriptom

NIAID Data Ecosystem10

FACT maintains pluripotency factor expression through gene-distal regulation in embryonic stem cells [RNA-seq]. FACT maintains pluripotency factor expression through gene-distal regulation in embryonic stem cells [RNA-seq]

胚胎干细胞多能性

FACT复合物

The mammalian FACT complex is a highly conserved histone chaperone with essential roles in transcription elongation, histone deposition, and maintenance of stem cell state. FACT is essential for viabi

NIAID Data Ecosystem10

RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription. RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription

RNA聚合酶转录

胚胎干细胞多能性

ChIP-seq experiments of NELFB (HA), NELFE, and Spt5 in mESCs under serum/LIF conditions. The experiments where performed with and without dTAG degradation of NELFB Overall design: Duplicates per condi

NIAID Data Ecosystem40

The Elongation Factor and Histone Chaperone Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Repressive Complex 2. Mus musculus

胚胎干细胞多能性

超级增强子与PRC2调控

Spt6 coordinates nucleosome dis- and re-assembly, transcriptional elongation and mRNA processing. Here, we report that depleting Spt6 in ESCs reduced expression of pluripotency factors, increased expr

NIAID Data Ecosystem10

Pluripotency Screen Paper

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