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Formal Substitution of Bromocyclopropanes with Nitrogen Nucleophiles

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NIAID Data Ecosystem2026-03-07 收录
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https://figshare.com/articles/dataset/Formal_Substitution_of_Bromocyclopropanes_with_Nitrogen_Nucleophiles/2391406
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A highly chemo- and diastereoselective protocol toward amino-substituted donor–acceptor cyclopropanes via the formal nucleophilic displacement in bromocyclopropanes is described. A wide range of N-nucleophiles, including carboxamides, sulfonamides, azoles, and anilines, can be efficiently employed in this transformation, providing expeditious access to stereochemically defined and densely functionalized cyclopropylamine derivatives.
创建时间:
2013-08-02
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