Thyroid dysgenesis (TD) is the common pathogenic mechanism of congenital hypothyroidism (CH). In addition, known pathogenic genes are limited to those that are directly involved in thyroid development
The database has sequence data obtained from Illumina HiSeq of rat epigenetic modifications across the genome. The rat strain is Sprague Dawley, and the rats are ten weeks of age. Sequenced tissues co
Taking full advantage of PacBio SMRT sequencing used for the genome assembly and detected DNA methylation on a genome-wide scale and analyzing all base modifications to determine modified sequence mot