Rh(III)-Catalyzed C(7)–H Alkylation of Quinolines in the Synthesis of Angular π‑Extended Pyrroloquinolines for Single-Component White-Light Emission

Reported
herein is a sustainable approach for a regioselective,
Rh­(III)-catalyzed C(7)–H alkylation of 8-aminoquinolines via
metal carbene migratory insertion. This transformation displays a
high functional group tolerance and exquisite site selectivity to
afford the C–7 alkylated products. These products are derivatized
to afford π-extended angular pyrroloquinolines, one of which
(4h) shows white-light emission (WLE) with CIE coordinates
(0.26, 0.34). An excellent cell viability and in vivo cellular imaging substantiate the nontoxic nature of these compounds.