Resistance to protease inhibitors and replicative capacity of Gag-recombinant proviral clones.

Numbers are the mean of at least three independent experiments��SD.Bold numbers indicate that the difference between AS or XS values and BS values was found statistically significant using a one-way ANOVA followed by Bonferroni's multiple comparison post-test.*Resistance is expressed as a fold-change in IC50 relative to pNL4-3, as described in Materials and Methods.**Replicative capacity (RC) is expressed as a % of pNL4-3 RC, as described in Materials and Methods.IDV, indinavir; NFV, nelfinavir; APV, amprenavir; SQV, saquinavir; LPV, lopinavir; ATV, atazanavir.