Dataset on transcriptome signature of skeletal muscle of young, adult and aged mice

Skeletal muscle aging is characterized by a progressive decline in muscle mass and function, which is referred to as sarcopenia. However, the molecular mechanisms implicated in sarcopenia remain unclear. In this dataset, we include the expression data obtained from gastrocnemius muscle of young, mature adult and old C57BL6 male mice. 18 Total samples were analyzed. Data were processed using GeneSpring GX 14.9 13 (Agilent) and analyzed by oneway ANOVA followed by pairwise comparisons using Tukey HSD post Hoc test. Benjamini-Hochberg multiple testing correction were performed to identify differentially expressed entities with a significance threshold set at P < 0.05. We generated the following pairwise comparisons using : 2 months vs. 11 months, 11 months vs. 25 months, 2 months vs. 25 months.