Gut microbiome of subjects with inflammatory bowel disease undergoing diet intervention

Inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, are chronic recurrent inflammatory disorders of the gastrointestinal tract affecting roughly 1 in 200 people in the US. There is an increasing interest in developing microbiome-centered therapies to treat IBD. Given that diet can rapidly shape the gut microbiome, dietary interventions may produce beneficial microbiome shifts. Participating subjects adopted the IBD Anti-inflammatory diet developed by the UMass Medical School Center for Applied Nutrition. The influence of diet on the microbiome and disease was assessed.