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Translating Dosage Compensation to Trisomy 21
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2013-07-12
相关数据集
Simplified assessment of central auditory processing in individuals presented with trisomy 21
ABSTRACT Purpose: to analyze the performance of individuals with trisomy 21 (T21) in the simplified assessment of central auditory processing, identify the impaired skills, and compare it with the res
DataCite Commons2022-06-07 更新80
Negative trade-offs shape the evolution of dosage sensitivity
Dominance is a relationship between alleles of a given gene, in which the fitness effect of one allele masks the contribution of the second allele. The evolutionary forces shaping dominance have been
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Sequence variation within similar cis-elements promotes context-specific functions of two Drosophila GA-binding transcription factors (ChIP-seq data set)
A key model for understanding how large transcription complexes are targeted is the Drosophila dosage compensation system in which the Male-Specific Lethal (MSL) transcription complex specifically ide
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Binding of an X-specific condensin correlates with a reduction in active histone modifications at gene regulatory elements. Binding of an X-specific condensin correlates with a reduction in active histone modifications at gene regulatory elements
Condensins are evolutionarily conserved protein complexes that are required for chromosome segregation during cell division and genome organization during interphase. In C. elegans, a specialized cond
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Domains of genomewide gene expression dysregulation in Down syndrome [RRBS]
Trisomy 21 (T21) is the most frequent genetic cause of cognitive impairment. To assess the perturbations of gene expression in T21, and to eliminate the noise of the genomic variability, we studied th
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