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Overexpression of<b> </b>the transcriptional activators Mxr1 and Mit1 enhances lactic acid production on methanol in <i>Komagataella phaffii</i>

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NIAID Data Ecosystem2026-05-02 收录
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The presence of lactic acid has a repressive effect on methanol utilizing genes in Komagataella phaffii Overexpression of the transcription factor genes MXR1 and MIT1 leads to higher expression of AOX1 and FDH1 and improves lactic acid production on MeOH in bioreactor cultivations Keeping MeOH concentration at 2 % is beneficial for lactic acid production

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2024-07-25
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