Structure of AKT1(WT) with compound 3
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Structure of AKT1(WT) with compound 3 Descriptor: 1,2-ETHANEDIOL, 4-{2-[({4-[(2P)-2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde, NB41, ... Authors: Craven, G.B, Taunton, J. Deposit date: 2023-11-06 Release date: 2024-09-04 Last modified: 2025-01-08 Method: X-RAY DIFFRACTION (1.972 Å) Cite: Mutant-selective AKT inhibition through lysine targeting and neo-zinc chelation. Nature, 637, 2025
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2023-11-06
