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Bace-1 in complex with a norstatine type inhibitor

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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Bace-1 in complex with a norstatine type inhibitor Descriptor: 3-[[(2S)-2-[[[(2S)-2-[[(2S)-2-[[(2S)-2-azanyl-3-(1H-1,2,3,4-tetrazol-5-ylcarbonylamino)propanoyl]amino]-3-methyl-butanoyl]amino]-4-methyl-pentanoyl]amino]methyl]-2-hydroxy-4-phenyl-butanoyl]amino]benzoic acid, Beta-secretase 1 Authors: Lindberg, J.D, Borkakoti, N, Derbyshire, D, Nystrom, S. Deposit date: 2009-12-07 Release date: 2010-12-29 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Investigation of a-phenylnorstatine and a-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibiotrs To be Published

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2009-12-07
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