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<b>In situ Perturb-seq applied to A375 melanoma tumors</b>

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NIAID Data Ecosystem2026-05-10 收录
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In situ Perturb-seq is a method for pooled optical genetic screens with spatial transcriptomics readouts in the intact tissue. Here in situ Perturb-seq was applied to A375 melanoma tumors in NSG mice to investigate top T cell receptor (TCR)-specific immunomodulating hits identified in the melanoma CRISPR activation screens.

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2026-02-19
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