Crystal Structure of human DOT1L in complex with inhibitor FED1
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Crystal Structure of human DOT1L in complex with inhibitor FED1 Descriptor: 5'-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5'-deoxyadenosine, Histone-lysine N-methyltransferase, H3 lysine-79 specific, ... Authors: Wernimont, A.K, Tempel, W, Yu, W, Li, Y, Nguyen, K.T, Federation, A, Marineau, J, Qi, J, Vedadi, M, Bradner, J.E, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brown, P.J, Structural Genomics Consortium (SGC) Deposit date: 2012-04-19 Release date: 2012-05-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun, 3, 2012
创建时间：
2012-04-19
