Performance evaluation of circulating IL-18 as a radiation biomarker in mouse serum.

Data were analyzed using IBM-SPSS program (SPSS Statistics Professional). A rough guide for assessing the utility of a biomarker based on its AUC is as follows: 0.9–1.0 = excellent; 0.8–0.9 = good; 0.7–0.8 = fair; 0.6–0.7 = poor; 0.5–0.6 = fail [31].ANOVA p-value and ROC analysis AUC at 95% CI: 0 Gy vs. all radiation doses (5, 7, 8, 9, 10, and 12 Gy).Performance evaluation of circulating IL-18 as a radiation biomarker in mouse serum.