five

Crystal structure of HDAC8 in complex with compound 2

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Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Crystal structure of HDAC8 in complex with compound 2 Descriptor: Histone deacetylase 8, N-{2-[3-(hydroxyamino)-3-oxopropyl]phenyl}-3-(trifluoromethyl)benzamide, POTASSIUM ION, ... Authors: Zheng, X, Conti, C, Caravella, J, Zablocki, M.-M, Bair, K, Barczak, N, Han, B, Lancia Jr, D, Liu, C, Martin, M, Ng, P.Y, Rudnitskaya, A, Thomason, J.J, Garcia-Dancey, R, Hardy, C, Lahdenranta, J, Leng, C, Li, P, Pardo, E, Saldahna, A, Tan, T, Toms, A.V, Yao, L, Zhang, C. Deposit date: 2019-03-26 Release date: 2020-04-01 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.88 Å) Cite: Structure-based Discovery of Novel N-(E)-N-Hydroxy-3-(2-(2-oxoimidazolidin-1-yl)phenyl)acrylamides as Potent and Selective HDAC8 inhibitors To Be Published
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2019-03-26
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