Table 1 in Metabolomic profiling of Zanthoxylum species: Identification of anticholinesterase alkaloids candidates

Table 1 Extracts of Zanthoxylum species analyzed in the metabolomic profiling and tested against AChE and BChE. Extracts showing IC values <100 μg mL −1 were 50 considered active (+).
Sample codeSpeciePlace of collectionPart/ExtractIC (μg mL −1) 50Ee AChEEq BChE1CZ. schreberi (J.F. Gmel.) ReynelTenaBark/chloroform14.11 ± 0.0644.94 ± 0.491ABark/aqueous478.0 ± 2.6203.5 ± 4.92CRoot bark/chloroform8.44 ± 0.0428.07 ± 0.242ARoot bark/aqueous206.3 ± 0.8261.9 ± 8.13CRoot/chloroform24.98 ± 0.1156.21 ± 0.643ARoot/aqueous623.8 ± 4.4267.4 ± 7.64CZ. rhoifolium Lam.ViotáRoot bark/chloroform9.67 ± 0.0522.38 ± 0.194ARoot bark/aqueous363.8 ± 2.690.23 ± 1.635CBark/chloroform24.39 ± 2.50351.9 ± 2.55ABark/aqueous294.2 ± 1.2> 10006CZ. caribaeum Lam.ViotáBark/chloroform187.5 ± 1.169.71 ± 0,696ABark/aqueous334.2 ± 2.0324.3 ± 0.97CRoot/chloroform92.30 ± 0.80135.7 ± 1.07ARoot/aqueous206.7 ± 1.6501.2 ± 1.28CZ. rigidum Humb. & Bonpl. ex WilldApuloBark/chloroform246.9 ± 1.3111.9 ± 1.78ABark/aqueous782.1 ± 1.3359.9 ± 9.49CRoot/chloroform23.33 ± 0.1045.47 ± 0.429ARoot/aqueous300.8 ± 1.5110.9 ± 1.510CZ. martinicense (Lam) DC.ApuloBark/chloroform24.29 ± 0.17172.70 ± 2.6610ABark/aqueous119.5 ± 8.830.71 ± 7.7411CRoot/chloroform24.29 ± 0.1748.22 ± 0.4111ARoot/aqueous729.0 ± 5.7> 100012CZanthoxylum spApuloBark/chloroform36.06 ± 0.2460.57 ± 0.5212ABark/aqueous187.2 ± 2.6245.9 ± 3.613CRoot/chloroform335.8 ± 1.9131.8 ± 1.213ARoot/aqueous138.0 ± 7.0171.8 ± 14.618CZ. caribaeum Lam.ViotáBark/chloroform211.9 ± 1.3333.5 ± 1.918ABark/aqueous207.9 ± 19.123.01 ± 1.0619CRoot/chloroform67.57 ± 0.37149.7 ± 0.419ARoot/aqueous76.29 ± 0.58429.3 ± 0.420CZ. monophyllum (Lam.) P. WilsonArbeláezRoot/chloroform5.01 ± 0.31130.9 ± 1.421CZ. quinduense Tul.TenaRoot/chloroform5.67 ± 0.4911.40 ± 0.3821ARoot/aqueous124.5 ± 10.0340.9 ± 8.522CZ. fagara (L.) Sarg.TocaimaBark/chloroform574.4 ± 2.9142.1 ± 0.822ABark/aqueous> 1000787.6 ± 13.923CZ. rhoifolium Lam.Guayabal de SiquimaBark/chloroform193.2 ± 1.3138.5 ± 1.323ABark/aqueous623.0 ± 7.6279.5 ± 2.724CWood/chloroform344.5 ± 2.8245.2 ± 2.124AWood/aqueous499.1 ± 5.7> 100025CZ. rhoifolium Lam.Santa Barbara (S/der)Bark/chloroform94.4 ± 0.9351.9 ± 0.325ABark/aqueous657.0 ± 11.2285.8 ± 3.4
IC 50 values are shown as the mean ± SEM of three independent experiments performed at least in duplicate.