AMPK signaling for naïve pluripotency [Hs]
收藏NIAID Data Ecosystem2026-04-30 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP095513
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资源简介：
We show activation of AMP kinase (AMPK) with single chemical compounds can endow naïve pluripotency. AMPK activators reverted early-stage differentiating cells or epi-stem cells to naïve state. Moreover, AMPK activators reverted human ESCs to naïve state with pluripotent gene expression profiles and X-chromosome reactivation. Overall design: We analyzed gene expression profiles of human ESCs with AICAR during differentiation and reversion
创建时间：
2023-01-11
