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Inhibition of neddylation causes developmental arrested in mouse embryos

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NIAID Data Ecosystem2026-03-13 收录
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The mechanism of maternal protein degradation in preimplantation embryos is not fully understood. It is currently believed that maternal proteins are mainly degraded by the ubiquitin-proteasome system. Our work provides new insights into new forms of ubiquitination in regulating mammalian embryo development, and may contribute to further investigation of female infertility pathology.

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2022-03-30
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