Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143
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Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, methyl 3-chloro-5-[(4,6-difluoro[1,1'-biphenyl]-3-yl)sulfamoyl]-4-hydroxybenzoate Authors: Wei, J, Tong, L. Deposit date: 2019-02-16 Release date: 2019-04-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: An allosteric mechanism for potent inhibition of human ATP-citrate lyase. Nature, 568, 2019
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2019-02-16
