Viral genomic tools assessment on HCMV two strain lab mixtures

Numerous genome assemblers and variants callers were evaluated on HCMV strain mixtures. The mixtures include TB40/E and Merlin (TM), TB40/E and AD169 (TA) with different mixture ratio namely 1:1, 1:10 and 1:50. The single strain WGS samples: TB40/E, Merlin and AD169 were also available here. The aim of this study is to provide guidance for building optimal viral genomic analysis pipeline of HCMV as well as other large DNA viruses.