Shmt2

ENCODES a protein that exhibits amino acid binding (ortholog); chromatin binding (ortholog); glycine hydroxymethyltransferase activity (ortholog); INVOLVED IN glycine biosynthetic process (ortholog); glycine biosynthetic process from serine (ortholog); glycine metabolic process (ortholog); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; folate cycle metabolic pathway; ASSOCIATED WITH cataract 15 multiple types (ortholog); Charcot-Marie-Tooth disease axonal type 2U (ortholog); familial melanoma (ortholog); FOUND IN BRISC complex (ortholog); cytoplasm (ortholog); microtubule cytoskeleton (ortholog)

编码一种具有氨基酸结合（同源物）、染色质结合（同源物）、甘氨酸羟甲基转移酶活性（同源物）特性的蛋白质；参与甘氨酸生物合成过程（同源物），包括由丝氨酸合成甘氨酸的过程以及甘氨酸代谢过程（同源物）；参与二氢嘧啶脱氢酶缺乏途径、二甲甘氨酸脱氢酶缺乏途径、叶酸循环代谢途径；与15种类型的白内障（同源物）、Charcot-Marie-Tooth病轴突型2U（同源物）、家族性黑色素瘤（同源物）相关；存在于BRISC复合体（同源物）、细胞质（同源物）、微管细胞骨架（同源物）中。