DNMT3A is frequently mutated in acute myeloid leukemia (AML). To recapitulate the features of human AML with hotspot DNMT3A R882H mutation, we generated Dnmt3a R878H conditional knock-in mice, which d
Data are mean±SEM. No abnormalities or significant differences between WT and iPLA2γ-KO mice were observed for hematologic parameters (n = 4–5).MPV indicates mean platelet volume.Hematological paramet
Whole blood was drawn by retro-orbital puncture and analyzed on an Advia120 whole blood analyzer. All values are+or – standard error of the mean. *Based on the Bonferonni correction for multiple obser
