Cryo-EM structure of 5HT3A receptor in presence of Palonosetron

Cryo-EM structure of 5HT3A receptor in presence of Palonosetron Descriptor: (3~{a}~{S})-2-[(3~{S})-1-azabicyclo[2.2.2]octan-3-yl]-3~{a},4,5,6-tetrahydro-3~{H}-benzo[de]isoquinolin-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(4-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Basak, S, Chakrapani, S. Deposit date: 2020-03-04 Release date: 2021-01-13 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: High-resolution structures of multiple 5-HT 3A R-setron complexes reveal a novel mechanism of competitive inhibition. Elife, 9, 2020