Pharmacodynamic parametersa describing the antimicrobial activity of marbofloxacin against different inoculum sizes of M. haemolytica (MH) and P. multocida (PM) in BHIB.
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a Mean ±SE of parameters calculated with Eqs 2 and 3 (sigmoid Emax model)b Antibiotic concentration reducing by 3 log10 the basal inoculum of 105 CFU/mLcAntibiotic concentration reducing by 5 log10 the basal inoculum of 108 CFU/mLd Sigmoid coefficient of the curve.e Maximal growth compared to the basal inoculum.f Minimal growth (maximal killing) compared to the basal inoculum.Pharmacodynamic parametersa describing the antimicrobial activity of marbofloxacin against different inoculum sizes of M. haemolytica (MH) and P. multocida (PM) in BHIB.
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2015-12-03
