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Conjugate Addition-Initiated Nazarov Cyclization

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Figshare2016-02-23 更新2026-04-29 收录
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A reaction sequence involving the 1,6-conjugate addition of a nucleophile to a dienyl diketone followed by Nazarov cyclization is described. Several nucleophiles are identified as competent initiators for the sequence. A different reaction outcome is observed when catalytic amounts of nucleophile are employed, involving elimination of the nucleophile after the electrocyclization.

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2016-02-23
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