Additional file 4 of MicroRNA and mRNA profiling in the idiopathic inflammatory myopathies

Additional file 4 GOseq analysis of differentially expressed genes in idiopathic inflammatory myopathy patients versus controls PM Polymyositis, DM Dermatomyositis, IBM Inclusion body myositis, Anti-Jo1 Subset of PM and DM with anti-Jo1 autoantibodies GOseq analysis was performed on significantly differentially expressed genes (FDR < 0.05) from RNA sequencing of 7 PM, 7 DM, 5 IBM and 5 control whole blood samples. The anti-Jo1 subgroup consists of 4 PM and 1 DM sample positive for anti-Jo1 autoantibodies. Columns are gene ontology category, p-value for over-representation, Benjamini Hochberg adjusted p-value for over-representation (FDR < 0.05 considered significant), p-value for under-representation, number of differentially expressed genes in that category, total number of genes in the gene ontology category, description of gene ontology category (term) and type of ontology (BP biological process, MF molecular function, CC cellular component).