Cis-Regulatory Element Hijacking by Structural Variants Overshadows Topological Changes in Primary Prostate Cancer. Cis-Regulatory Element Hijacking by Structural Variants Overshadows Topological Changes in Primary Prostate Cancer

顺式调控元件劫持

Prostate cancer is a heterogeneous disease whose progression is linked to genome instability. However, the impact of this instability on the non-coding genome and its three-dimensional organization to

NIAID Data Ecosystem40

BCL11B enhancer hijacking defines a subtype of lineage ambiguous stem cell leukemia. BCL11B enhancer hijacking defines a subtype of lineage ambiguous stem cell leukemia

白血病基因组

增强子劫持机制

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem30

Cohesin protein STAG2 regulates expression of IRF9 and interferon signaling in melanoma via enhancer loop reprogramming [HiChIP]. Cohesin protein STAG2 regulates expression of IRF9 and interferon signaling in melanoma via enhancer loop reprogramming [HiChIP]

癌症三维基因组学

肿瘤信号通路

The cohesin complex participates in the organization of 3D genome through generating and maintaining DNA loops. Stromal antigen 2 (STAG2), a core subunit of the cohesin complex, is frequently mutated

NIAID Data Ecosystem20

3D genomic analysis reveals novel enhancer-hijacking caused by complex structural alterations that drive oncogene overexpression. 3D genomic analysis reveals novel enhancer-hijacking caused by complex structural alterations that drive oncogene overexpression

资源简介：

3D genomic analysis reveals novel enhancer-hijacking caused by complex structural alterations that drive oncogene overexpression. 3D genomic analysis reveals novel enhancer-hijacking caused by complex structural alterations that drive oncogene overexpression

资源简介：

相关数据集