Crystal structure of the VEGFR2 kinase domain in complex with a pyridone inhibitor
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Crystal structure of the VEGFR2 kinase domain in complex with a pyridone inhibitor Descriptor: 3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one, Vascular endothelial growth factor receptor 2 Authors: Whittington, D.A, Long, A.M, Rose, P, Gu, Y, Zhao, H. Deposit date: 2008-03-31 Release date: 2008-06-17 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit. J.Med.Chem., 51, 2008
创建时间：
2008-03-31
