Mucosal and humoral response data gathered from specific-pathogen-free chickens inoculated with avian influenza subtype H9N2 and Bacillus cereus

These data present the results and data underlying the figures of the related study - <i>Contaminated feed-borne Bacillus cereus aggravates respiratory distress post avian influenza virus H9N2 infection by inducing pneumonia</i> - in which the humoral and mucosal responses of specific-pathogen-free (SPF) chickens to <i>Bacillus cereus</i> and avian influenza A subtype H9N2 coinfection were evaluated.<br>Data are presented in an XLSX file and are arranged based on their associated figure and specific panel therein from the accompany paper. Data are further grouped based on the 5 study groups observed:<br>* SPF chicks inoculated with <i>B. cereus</i> followed by H9N2 (n=21)* SPF chicks inoculated with H9N2 followed by <i>B. cereus </i>(n=21)* SPF chicks inoculated with <i>B. cereus </i>only (n=21)* SPF chicks inoculated with H9N2 only (n=21)* Control (n=21)<br>The contents of the data provided are listed below by their associated figure and containing sheet within the XLSX file:<br><b>Figure 1</b><b>A.</b> Mean body weights across each study group pre-inoculation. <b>B.</b> Mean body weights across each group and 7, 14 and 21 days post-inoculation.<b><br></b><b>Figure 4</b><b>A.</b> Scoring of air sac lesions present across each study group (as per Table 1 of the accompanying paper) at 14 and 21 days post-inoculation.<b>B. </b>Scoring of lung inflammation present across each study group (as per Table 1 of the accompanying paper) at 14 and 21 days post-inoculation. <b><br></b><b>Figure 5</b><b>A.</b> H9N2 viral load at days 14 and 21 post-inoculation compared to <i>B. cereus</i> / H9N2 and H9N2 / <i>B. cereus</i> groups.<b>B.</b> <i>B. cereus</i> load at days 14 and 21 post-inoculation compared to <i>B. cereus</i> / H9N2 and H9N2 / <i>B. cereus</i> groups<b><br></b><b>Figure 6</b><b>A.</b> Newcastle Disease Virus (NDV)-specific antibody levels for each study group at 7, 14 and 21 days post-inoculation.<b>B.</b> Non-specific IgA antibody levels for each study group at 7, 14 and 21 days post-inoculation.<b><br></b><b>Figure 7</b>Lymphocyte proliferation indices for each study study group at 7 and 14 days post-inoculation.<b><br></b><b>Figure 8</b><b>A. </b>IL-2 expression for each study study group at 7 and 14 days post-inoculation.<b>B. </b>IL-6 expression for each study study group at 7 and 14 days post-inoculation.<b>C. </b>IL-γ expression for each study study group at 7 and 14 days post-inoculation.<b>D. </b>IL-12 expression for each study study group at 7 and 14 days post-inoculation.