five

Wee1 kinase complex with inhibitor PD331618

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Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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Wee1 kinase complex with inhibitor PD331618 Descriptor: 4-(2-chlorophenyl)-8-[3-(dimethylamino)propoxy]-9-hydroxy-6-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione, CHLORIDE ION, Wee1-like protein kinase Authors: Squire, C.J, Dickson, J.M, Ivanovic, I, Baker, E.N. Deposit date: 2007-12-02 Release date: 2007-12-25 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases. Bioorg.Med.Chem.Lett., 18, 2008
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2007-12-02
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