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Crystal structure of human TRIM21 PRYSPRY in complex with T-02

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Protein Data Bank Japan2025-08-13 更新2026-05-24 收录
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Crystal structure of human TRIM21 PRYSPRY in complex with T-02 Descriptor: 1-ethyl-~{N}-methyl-5-phenyl-~{N}-[3-[3-(trifluoromethyl)phenyl]cyclobutyl]pyrazole-4-carboxamide, E3 ubiquitin-protein ligase TRIM21 Authors: Zhang, L.J, Zhang, L.Y. Deposit date: 2025-03-03 Release date: 2025-07-16 Last modified: 2025-08-13 Method: X-RAY DIFFRACTION (2.08 Å) Cite: TRIM21-Driven Degradation of BRD4: Development of Heterobifunctional Degraders and Investigation of Recruitment and Selectivity Mechanisms. J.Chem.Inf.Model., 65, 2025

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2025-03-03
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