CHROMOBACTERIUM VIOLACIUM INDUCED UTI IN A FREQUENTLY RELAPSING NEPHROTIC SYNDROME: A CASE REPORT

A 9 year old boy with frequently relapsing nephrotic syndrome presented to paediatric department with complaints of periorbital oedema, decreased urine output, anorexia & abdominal pain. His vitals were stable with heavy proteinuria. He developed urinary tract infection by Chromobacterium violaceum. He was treated successfully with 1 gm% IV Ceftriaxone. Chromobacterium violaceum is a gram negative, oxidase positive, anaerobic, beta proteobacterium causing human infections infrequently. Found in tropical & subtropical regions as normal flora of water & soil. Around 150 cases of C violaceum was reported worldwide. Usually causes skin & soft tissue infections, visceral abscesses, meningitis, diarrhea, urinary tract infection, septicaemia etc. The organism is resistant to penicillin, narrow-spectrum cephalosporin, amoxicillin-clavulanic acid, polymyxin B & sensitive to fluoroquinolones, carbapenems, cotrimoxazole, chloramphenicol, aminoglycosides, etc. Delayed proper treatment due to limited awareness is responsible for high mortality rate. This case was reported for its rare clinical presentation being the first case to be described from a tertiary care centre of Arunachal Pradesh, North-East India.