Additional file 9 of Pathological mechanisms and candidate therapeutic approaches in the hearing loss of mice carrying human MIR96 mutations

Additional file 9: Table S8. Input and output from the SPIED tool. The transcriptomes from Mir96 +13G>A and Mir96 +14C>A homozygotes were combined by excluding genes misregulated in opposite directions. The resulting list, used as input for SPIED, is shown on the left sub-table. The SPIED output for this list is shown in the middle sub-table, and the SPIED output for the Mir183/96 dko transcriptome alone [12] is shown in the right sub-table. Output columns show the compound, tissue and stage of each correlated or anti-correlated DrugMatrix expression profile, the correlation score of the input transcriptome data with that DrugMatrix expression profile, the z-score of that correlation (the highest z-score is the best-correlated profile) and the number of genes from the input transcriptome present in the DrugMatrix expression profile.