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CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site

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Protein Data Bank Japan2023-12-27 更新2026-03-21 收录
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CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site Descriptor: 4-{3-[7-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2, Cyclin-A2, ... Authors: Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X. Deposit date: 2008-11-04 Release date: 2009-02-03 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor. Bioorg.Med.Chem.Lett., 19, 2009

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2008-11-04
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