Figure S1 - DC-SIGN Mediated Sphingomyelinase-Activation and Ceramide Generation Is Essential for Enhancement of Viral Uptake in Dendritic Cells
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DC-SIGN blocking interferes with MV binding to DCs. DCs were pretreated with mannan at the concentrations indicated, a DC-SIGN-specific antibody (H200) (10 µg/ml) or 10 mM EGTA prior to MV exposure (m.o.i. 2). Percentages of cells staining for MV F protein and mfis were determined by flow cytometry following a 1hrs incubation period on ice. (0.45 MB EPS)
创建时间:
2011-02-17



