Structure of the human GluN1/GluN2A LBD in complex with compound 2 (GNE9178)
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Structure of the human GluN1/GluN2A LBD in complex with compound 2 (GNE9178) Descriptor: 7-{[5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-N-ethyl-2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide, ACETATE ION, CALCIUM ION, ... Authors: Wallweber, H.J.A, Lupardus, P.J. Deposit date: 2016-10-20 Release date: 2016-11-30 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.4 Å) Cite: GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. ACS Med Chem Lett, 8, 2017
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2016-10-20
