TCCSUP-Control/-Knockdown/-Knockout cells were incubated with DMEM/F12 supplemented with B27, N2, epidermal growth factor and basic fibroblast growth factor in the presence of ethanol (mock), 100 nmol

Figshare2019-10-23 更新60

Inhibiting WNT and NOTCH in renal cancer stem cells: implications for human patients

癌症干细胞研究

信号通路抑制

We detected and characterized CXCR4+MET+CD44+ cancer stem cells (CSCs) that were quantitatively correlated with aggressive tumors. Transcriptional profiling and single-cell sequencing revealed a stron

NIAID Data Ecosystem40

Single-cell transcriptomic analysis of mammary tumors reveals distinct patterns of hierarchical and subtype heterogeneity

单细胞肿瘤异质性分析

癌症干细胞研究

Breast cancer stem cells (BCSCs) contribute to intra-tumoral heterogeneity and therapeutic resistance. However, the binary concept of universal BCSCs co-existing with bulk tumor cells is over-simplifi

NIAID Data Ecosystem60

RNA-seq analysis of CD276-high/EpCAM+ cells from HNSCC patient-derived-xenograft. RNA-seq analysis of CD276-high/EpCAM+ cells from HNSCC patient-derived-xenograft

癌症干细胞研究

头颈鳞状细胞癌机制

We performed RNA sequencing (RNA-seq) to compare the gene expression pattern between CD276-high/EpCAM+ and CD276-low/EpCAM+ cells isolated from human HNSCC PDX. We identified a cohort of key oncogenes

NIAID Data Ecosystem50

BEX2 is poor prognostic factor and required for cancer stemness in gastric cancer [MKN1_siBEX2]

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