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资源简介：
iPSC CRISPR-Cas9 engineered lines.
应用场景：
创建时间：
2022-10-27
相关数据集
Rescue of Male Infertility through Correcting a Genetic Mutation Causing Meiotic arrest in Spermatogonial Stem Cells [RNA-seq]
Azoospermia patients who carry a monogenetic mutation that causes meiotic arrest may have their biological child through genetic correction in spermatogonial stem cells (SSCs). However, such therapy f
NIAID Data Ecosystem110
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells
When loss of heterozygosity (LOH) is correlated with loss or gain of disease phenotype, it is often necessary to identify which gene or genes are involved. Here, we generated a region-specific LOH-ind
NIAID Data Ecosystem60
Mutation of smarca5 in zebrafish leads to venous thrombosis-like phenotype. Danio rerio
Our study using zebrafish smarca5 mutants both characterizes a novel role for smarca5 in blood clot formation and also provides a new venous thrombosis animal model to support drug screening and pre-c
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whole genome sequencing of TAM-edited iPSCs
To determine the off-target mutagenesis of TAM in iPSCs
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Unraveling MLL1-fusion Leukemia: Epigenetic Revelations from an iPS Cell Point Mutation
Human iPS cells (WT ASE9203 cells) were obtained from Applied Stem Cell (ASC), and CRISPR-Cas9-mediated gene editing was completed by ASC using their proprietary CRISPR-Cas9 protocol to introduce the
NIAID Data Ecosystem60
