Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in liver

Data Content

In this data repository Ultra High-Performance Chromatography (UPLC) and Ion Chromatography (IC)- high resolution mass spectrometry (HRMS) metabolomic data is provided. The data consists of all analyzed raw files and the associated peak picking files (TraceFinder 5.1, Thermo Fisher Scientific). The data with the abreviation "Bz_QE_Plus" contains the UPLC-MS data of bezoylchloride derivatized amines, phenols, thiols, and some alcohols measured on a Q-Exactive Plus mass spectrometer), while the files with the abbreviation "IC_HF_TF" contain the anion chromatographic data measured on a Q-Exactive Plus coupled to an Integrion ion chroatograph.

The provided data is associated to an article submitted to Nature Communications (“Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in liver”), describing the analysis of COX14 and COA3 mutants (see abstract below).

The sample and data analysis section, which is also provided in the supplementary section of the above mentioned article, are also attached as, doc files to the deposited data.