官方服务:
资源简介:
Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection
应用场景:
创建时间:
2023-08-26
相关数据集
The RNA architecture of the SARS-CoV-2 3-prime untranslated region
SARS-CoV-2 is responsible for the COVID-19 pandemic. We used a chemical probing technique namely DMS-MaP to elucidate the structure of the 3-prime untranslated region (3 UTR) of the viral RNA genome.
NIAID Data Ecosystem60
Fitness of FMDV 3D(SSI) relative to FMDV Wt in the presence of R, FU, or a mixture of R and FU.
aGrowth-competition experiments were initiated by infecting 2×106 BHK-21 cells with 7×105 PFU of FMDV Wt and FMDV 3D(SSI) in the absence of drugs or in the presence either of 5000 µM R, 2000 µM FU or
NIAID Data Ecosystem30
Functional and Genetic Analysis of Coronavirus Replicase-Transcriptase Proteins
The coronavirus replicase-transcriptase complex is an assembly of viral and cellular proteins that mediate the synthesis of genome and subgenome-sized mRNAs in the virus-infected cell. Here, we report
Figshare2016-01-18 更新10
hnRNP C modulates MERS-CoV and SARS-CoV-2 replication by governing the expression of a subset of circRNAs and cognitive mRNAs
Host circular RNAs (circRNAs) play critical roles in the pathogenesis of viral infections. However, how viruses modulate the biogenesis of host proviral circRNAs to facilitate their replication remain
NIAID Data Ecosystem50
Defining the Impact of Getah Virus Envelope Protein Glycosylation Site Mutations on Viral Replication, Host Adaptation, Virulence, and Immune Evasion
Getah virus (GETV) is an emerging mosquito-borne alphavirus that causes significant animal outbreaks. Epidemic strains possess a unique N-glycosylation site (E2-N262) absent in historical lineages. Th
科学数据银行2025-11-08 更新20



