Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont: ECF mutant

Growth of isogenic parent ('tdk strain'), 5xECF-sigma factor mutant and complemented mutant strain in the cecum of NMRI inbred mice fed a glycan-restricted, 'simple sugar' diet (35% each glucose and sucrose). Bacteria were collected from mouse distal gut 10 days after colonization. Experiment performed in biological triplicate; for purposes of cross-comparison, profiles were referenced to an in vitro minimal medium glucose chemostat culture (800ml volume, mid-log phase). Reference samples are GSM301635, 301637 and 301639 and are part of series GSE11944.