TCF4 is a key mediator of cell identity in neuroblastoma and vulnerable to protein degradation by multiple epigenetic factors

NIAID Data Ecosystem2026-05-02 收录

神经母细胞瘤分子机制

表观遗传调控与蛋白质降解

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE222214 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2025-03-19

Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma [tumor_genex_44k]

神经母细胞瘤分子机制

HOX基因功能

Single-color gene expression profiles from 649 neuroblastoma tumors were generated using 44K oligonucleotide microarrays. We aimed at determining the association of class I HOX gene expression pattern

NIAID Data Ecosystem70

Transcriptomic analysis of neuroblastoma cells in response to stable over-expression of circular RNA derived from CUX1 gene (circ-CUX1)

神经母细胞瘤分子机制

环状RNA功能研究

Circular RNAs (circRNAs), a subclass of noncoding RNAs characterized by covalently closed continuous loops, play emerging roles in tumorigenesis and aggressiveness. However, the functions and underlyi

NIAID Data Ecosystem50

Transcriptomic changes in MYC and PRC2 targets are prominent events in the early pathogenesis of neuroblastoma in TH-MYCN mice

神经母细胞瘤分子机制

转录组学分析

It has been already reported that there are undifferentiated/proliferating neuroblasts in the postnatal sympathetic ganglia in TH-MYCN mice. We established suitable spheroid culture condition that sel

NIAID Data Ecosystem50

Datasheet1_Hsa-miR-323a-3p functions as a tumor suppressor and targets STAT3 in neuroblastoma cells.pdf

神经母细胞瘤分子机制

肿瘤抑制因子

BackgroundStudies conducted in the last decades have revealed a role for the non-coding microRNAs (miRNAs) in cancer development and progression. Several miRNAs within the chromosome region 14q32, a r

NIAID Data Ecosystem50

Genome wide differential gene expression analysis after DDX21 knockdown in MYCN-amplified human neuroblastoma BE(2)-C cells. Genome wide differential gene expression analysis after DDX21 knockdown in MYCN-amplified human neuroblastoma BE(2)-C cells

神经母细胞瘤分子机制

功能基因组学

Genome wide differential gene expression analysis after DDX21 knockdown by treatment with DOX in MYCN-amplified human neuroblastoma BE(2)-C cells stably transfected with DOX-indicible control shRNA, D

NIAID Data Ecosystem50

TCF4 is a key mediator of cell identity in neuroblastoma and vulnerable to protein degradation by multiple epigenetic factors

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