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Elucidation of the mechanisms underlying the therapeutic effects of cell therapy using hiPSC-NPCs

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP532143
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To identify factors contributing to the therapeutic efficacy of hiPSC-NPCs in a cisplatin-induced AKI mouse model, we performed RNA-seq on three samples each of human iPS cell-derived nephron progenitor cells (hiPSC-NPCs) that showed therapeutic efficacy and fate-specific hiPSC-NPCs (hiPSC-FS-NPCs) that showed reduced therapeutic efficacy. Overall design: Comparative gene expression profiling analysis of RNA-seq data from 4A6 cell line-derived hiPSC-NPCs and hiPSC-FS-NPCs (three biological replicates per group).
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2025-09-25
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