Synthesis and Biological Activity of Organoantimony(III)-Containing Heteropolytungstates

Three discrete organoantimony­(III)-containing heteropolytungstates [(PhSbIII)4(A-α-GeIVW9O34)2]12– (1), [(PhSbIII)4(A-α-PVW9O34)2]10– (2), and [{2-(Me2NCH2C6H4)­SbIII}3(B-α-AsIIIW9O33)]3– (3) have been synthesized in one-pot reactions in aqueous medium using the appropriate lacunary heteropolyanion precursor and organoantimony­(III) source. Polyanions 1–3 were isolated as hydrated salts, (NH4)12[(PhSbIII)4(A-α-GeIVW9O34)2]·20H2O (1a), Rb9Na­[(PhSbIII)4(A-α-PVW9O34)2]·20H2O (2a), and Rb3[{2-(Me2NCH2C6H4)­SbIII}3(B-α-AsIIIW9O33)]·7H2O (3a). The compounds 1a–3a were fully characterized in the solid state using infrared (IR) spectroscopy, single-crystal XRD, and thermogravimetric and elemental analyses. The stability of 1–3 in aqueous solution was confirmed by multinuclear NMR (1H, 13C, 31P, and 183W) spectroscopy. Preliminary studies on the biological activity of 1–3 showed that all three compounds might act as potent antimicrobial agents.