Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations

ChEBI2013-07-01 更新2026-07-21 收录

肺癌发生机制

细胞恶性转化

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-40828 数据链接链接失效反馈

官方服务：

资源简介：

Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations

创建时间：

2013-07-01

p300 suppresses the transition of myelodysplastic syndrome to acute myeloid leukemia [DIP-seq]. p300 suppresses the transition of myelodysplastic syndrome to acute myeloid leukemia [DIP-seq]

肿瘤表观遗传学

细胞恶性转化

The p300 lysine acetyltransferase (KAT) can function as an oncogene or a tumor suppressor in hematologic malignancies. We have identified a tumor suppressor role for p300 in myelodysplastic syndrome (

NIAID Data Ecosystem70

In vitro transformation of human bronchial epithelial cells by diesel exhaust particles

环境毒理学

细胞恶性转化

The potential of diesel exhaust particles (DEP) to transform human bronchial epithelial cells (HBEC3) was investigated and a stably transformed cell line (T2-HBEC3) was established. Short-term DEP exp

NIAID Data Ecosystem40

Temporal Dissection of K-rasG12D Mutant In Vitro and In Vivo Using a Regulatable K-rasG12D Mouse Allele

肺癌发生机制

基因功能时空调控

Animal models which allow the temporal regulation of gene activities are valuable for dissecting gene function in tumorigenesis. Here we have constructed a conditional inducible estrogen receptor-K-ra

Figshare2016-01-19 更新30

Silica-mediated airway chronic inflammation promotes lung carcinogenesis through the activation of preneoplastic lesions in the context of an immunosuppressive microenvirontment. Mus musculus

肺癌发生机制

炎症相关癌变

Basic studies on preneoplastic lesions are important to determine the molecular alterations that take place in early steps of lung carcinogenesis. Little is known about the molecular events preceding

NIAID Data Ecosystem40

Chromosomal instability suppresses the growth of K-Ras-induced lung adenomas

肺癌发生机制

染色体不稳定性

Chromosomal instability (CIN) is defined as a high rate of whole chromosome loss or gain and is a hallmark of many aneuploid solid tumors. CIN positively correlates with poor patient prognosis and che

Taylor & Francis Group2023-03-17 更新30

Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations

资源简介：

相关数据集