anglixue/TenK10K_multiome

该数据集提供了人类外周血单个核细胞（PBMCs）中遗传对染色质可及性影响的群体规模单细胞分辨率汇总统计，作为TenK10K计划的一部分生成。它包括来自922名供体的28种免疫细胞类型的染色质可及性QTL（caQTL）汇总统计，以及共定位结果、精细定位输出、ChromBPNet变异效应评分、细胞状态依赖性caQTL结果和基因调控网络推断输出。This dataset provides population-scale, single-cell resolution summary statistics of genetic effects on chromatin accessibility in human peripheral blood mononuclear cells (PBMCs), generated as part of the TenK10K program. It includes chromatin accessibility QTL (caQTL) summary statistics mapped across 28 immune cell types from 922 donors, alongside colocalization results, fine-mapping outputs, ChromBPNet variant effect scores, cell state-dependent caQTL results, and gene regulatory network inference outputs.